Posts

Painkillers without dangerous side effects

Image
Treating postoperative and continual inflammatory ache ought to now be potential with out inflicting uncomfortable side effects. Doing so would considerably enhance affected person high quality of life. (Inventory picture) Credit score: © imacoconut / Fotolia Researchers from Charité -- Universitätsmedizin Berlin have found a brand new means of growing painkillers. The group of researchers used computational simulation to research interactions at opioid receptors -- the cell's docking websites for painkillers. When utilized in an animal mannequin, their prototype of a morphine-like molecule was in a position to produce substantial ache reduction in infected tissues. Nevertheless, wholesome tissues remained unaffected, suggesting that the extreme uncomfortable side effects at present related to these kinds of painkillers could be prevented. This analysis has been revealed within the present challenge of the journal  Science . Opioids are a category of ...

New study sheds light on perceptions of e-cigs

The study of 105 U.S. Army Reserve and National Guard soldiers and their partners found that those study participants who vape daily reported e-cigarettes as "at least as satisfying" as cigarettes, and that 58 percent said vaping was "much more" satisfying. Researchers also reported that the perception of danger from e-cigarettes decreased as frequency of use increased. The paper was published online first in the journal Preventive Medicine Reports. "The results argue that satisfaction, perceived harm or danger and product type seem to all work together to promote use or avoidance," said Lynn Kozlowski, the paper's lead author and a professor of community health and health behavior in UB's School of Public Health and Health Professions. "The mistaken belief that e-cigarettes are more harmful than cigarettes can influence some smokers to not use e-cigs. If the type of product they use is less satisfying, this also can influence likelih...

Giving up cigarettes linked with recovery from illicit substance use disorders

Most adults who have illicit drug use disorders also smoke cigarettes. Yet while treatments for substance use disorders traditionally include and require concurrent treatment for addiction to all substances -- including treatment for and required abstinence from alcohol and any other illicit substance use -- treatment for nicotine dependence has not routinely been part of treatment for illicit substance use problems. "The thinking in clinical settings has been that asking patients to quit cigarette smoking while they try to stop using drugs is "too difficult," or that smoking may be helpful in remaining abstinent from alcohol and drugs, but it is not related whether or not one remains abstinent from illicit drug use over the long term," said Renee Goodwin, PhD, of the Department of Epidemiology , Mailman School of Public Health, who led the research. The researchers studied data from 34,653 adults enrolled in the National Epidemiologic Survey on Alcohol and R...

Consumption of alcohol and marijuana associated with lower GPA in college

Alcohol and marijuana are the two most abused substances in US colleges, but little is known about the effect of consuming both on students' academic performance. The authors of the present study examined the association between college students' alcohol and marijuana consumption and their grade point average (GPA) in each semester. They used data from the Brain and Alcohol Research in College Students study, which tracked 1,142 students for two years after they began college, and using self-reported data they clustered them into groups of low users or medium-to-high users of alcohol or both substances. Despite no differences in pre-college SAT scores, researchers found that students who were medium-to-high users of both substances not only had a lower predicted college GPA on average by the end of the first semester, but continued to achieve lower GPAs throughout the two years of the study. Those students who consumed medium-to-high levels of alcohol but little marijuana ...

Hard choices? Ask your brain's dopamine

Image
Blue signifies cell nuclei, inexperienced signifies dopamine neurons labeled with inexperienced fluorescent protein. Credit score: Salk Institute Say you are reaching for the fruit cup at a buffet, however on the final second you turn gears and seize a cupcake as a substitute. Emotionally, your determination is a fancy stew of guilt and mouth-watering anticipation. However bodily it is a easy shift: as a substitute of transferring left, your hand went proper. Such split-second modifications curiosity neuroscientists as a result of they play a significant position in illnesses that contain issues with choosing an motion, like Parkinson's and drug habit. Within the March 9, 2017 on-line publication of the journal  Neuron , scientists on the Salk Institute report that the focus of a mind chemical referred to as dopamine governs selections about actions so exactly that measuring the extent proper earlier than a call permits researchers to precisely predict ...

Marijuana use associated with increased risk of stroke, heart failure

Image
Coming at a time when marijuana, medically generally known as hashish, is on monitor to turn out to be authorized for medical or leisure use in additional than half of U.S. states, this examine sheds new gentle on how the drug impacts cardiovascular well being. Credit score: © tugolukof / Fotolia Utilizing marijuana raises the danger of stroke and coronary heart failure even after accounting for demographic components, different well being situations and life-style danger components corresponding to smoking and alcohol use, based on analysis scheduled for presentation on the American School of Cardiology's 66th Annual Scientific Session. Coming at a time when marijuana, medically generally known as hashish, is on monitor to turn out to be authorized for medical or leisure use in additional than half of U.S. states, this examine sheds new gentle on how the drug impacts cardiovascular well being. Whereas earlier marijuana analysis has targeted totally on pu...

Anxiety is a stronger harbinger of alcohol problems than stress

Recent drinking was assessed in 87 individuals (70 men, 17 women) with alcohol use disorders (AUDs). Three distinct measures were used to evaluate anxiety, anxiety sensitivity, and perceived stress. A subset of 30 subjects was admitted to a medical center to ensure alcohol abstinence for one week: measures of alcohol craving were collected twice daily. On day 4, subjects participated in a public speaking/math challenge, before and after which measures of cortisol and alcohol craving were collected. In these heavy drinkers, measures of anxiety as compared with perceived stress were more strongly associated with a variety of alcohol-related measures. While alcohol studies often use the terms anxiety , anxiety sensitivity, and stress interchangeably, this study showed the importance of differentiating among the three terms given their unique relationships with drinking, craving, and stress reactivity among individuals with AUDs . for more information visit our product website: B...